Hyaluronic Acid Injections May Delay Total Knee Replacement in Osteoarthritis

​At Physioimpulse we provide therapeutic injections in conjunction with Physiotherapy treatment to optimise recovery from injury and reduce pain in degenerative conditions such as Osteoarthritis.
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Injection therapy can benefit the following conditions:

• Osteoarthritis of the Knee, Shoulder, Thumb, Wrist or Ankle
• Frozen Shoulder
• Shoulder Impingement

Injections are performed by our Clinical Specialist Physiotherapist Matt Shepherd who has undertaken extensive Post Graduate training in order to carry out injections at our Bath Physiotherapy Clinics.

We are receiving some great feedback on the pain relieving effects of our Ostenil Plus injections which enable people to return to their normal activities of daily living with greatly reduced reports of pain.
The study below outlines the benefits of these injections in delaying the need for major knee surgery

If you would like to know more about these injections read our Injection Therapy page or email [email protected]

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The use of intra-articular hyaluronic acid (HA) injections in patients with osteoarthritis (OA) of the knee has shown efficacy in delaying total knee replacement (TKR) surgery in a recent retrospective, longitudinal study published in PLoS One.

The investigators sought to compare the delay from diagnosis to TKR surgery in patients with knee OA who received intra-articular HA injections vs those who did not. All patients studied were treated in France between 2006 and 2013. A second objective of the study was to compare direct medical costs associated with ambulatory care between the 2 groups.

A total of 14,782 patients were treated for knee OA (ages ≥50 years; mean age, 68±10 years; 67% women). Annual incidence rates of knee OA were estimated to be 0.52% in women and 0.92% in men. Of the 14,782 patients, 1662 individuals (11.2%) underwent TKR surgery before the end of 2013.

At each point evaluated, restricted mean survival time without TKR surgery was higher in the HA treatment vs no injection group (from 51 days at 1 year after diagnosis to 217 days at 7.5 years, respectively; P <.001). 
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This is the first retrospective longitudinal study involving patients with knee OA that used medico-administrative databases in France. The investigators concluded that “the results support the effectiveness of [HA] injections in delaying [TKR] surgery. 


Reference

Delbarre A, Amor B, Bardoulat I, et al. Do intra-articular hyaluronic acid injections delay total knee replacement in patients with osteoarthritis – A Cox model analysis. PLoS One. 2017;12(11):e0187227.

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